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projects [2020/07/03 11:16]
shyam [PaTH Clinical Data Research Network]
projects [2021/06/14 17:35]
shyam
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 ===== Projects ===== ===== Projects =====
  
-==== Informatics Core, CTSI ====+==== Biomedical Informatics Core, CTSI ====
 {{ wiki:ctsi.png?300x0}} {{ wiki:ctsi.png?300x0}}
  
-The Informatics Core of the [[http://www.ctsi.pitt.edu/|Clinical and Translational Science Institute (CTSI)]] has established a research data warehouse; developed and deployed user-friendly, web-based informatics tools such as a Cohort Discovery Tool and a Computable Phenotype Library Tool; and is developing a secure data analytic environment.+The Biomedical Informatics Core of the [[http://www.ctsi.pitt.edu/|Clinical and Translational Science Institute (CTSI)]] has established a research data warehouse; developed and deployed user-friendly, web-based informatics tools such as a Cohort Discovery Tool and a Computable Phenotype Library Tool; and is developing a secure data analytic environment.
  
 This work is funded by grant [[https://projectreporter.nih.gov/project_info_description.cfm?aid=9260460|UL1 TR001857]] from NCATS, NIH. This work is funded by grant [[https://projectreporter.nih.gov/project_info_description.cfm?aid=9260460|UL1 TR001857]] from NCATS, NIH.
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-==== National Mesothelioma Virtual Bank (NMVB) ==== +==== Genomic Information Commons (GIC) ====
-{{ wiki:nmvb.png?350x0}}+
  
-The [[http://mesotissue.org/|National Mesothelioma Virtual Bank (NMVB)]] is a virtual biospecimen registry designed to support and facilitate basic science, clinical, and translational research that will advance understanding of mesothelioma pathophysiology with the goal of expediting the discovery of preventive measures, novel therapeutic interventions, and ultimately, cures for mesotheliomaThe current participants in the virtual bank are University of PittsburghUniversity of PennsylvaniaNYU Langone Medical CenterRoswell Park Cancer Institute and University of Maryland.+The [[https://www.genomicinformationcommons.org/|Genomic Information Commons (GIC)]] is a federated network that is developing two portals for researchers: (A) Prep-to- research portalInvestigators can execute genotypephenotypeor combined genotype/phenotype queries, and receive aggregate results in real time; and (B) Study portal. With proper approvals, patient-level data are readily transferred to a cloud-hosted environment.
  
-This work is funded by grant [[https://projectreporter.nih.gov/project_info_description.cfm?aid=8931767|U24 OH010873]] from NIOSH, NIH.+This work is funded by [[https://projectreporter.nih.gov/project_info_description.cfm?aid=9818382|U01 grant]] from the NCATS, NIH.
  
  
  
-==== The TIES Cancer Research Network (TCRN) ==== +==== National Mesothelioma Virtual Bank (NMVB) ==== 
-{{ wiki:tcrn.png?200x0}} +{{ wiki:nmvb.png?350x0}}
- +
-The [[http://ties.dbmi.pitt.edu/|Text Information Extraction System (TIES) Cancer Research Network]]  is a federated network of clinical reports and biospecimen registry to support and facilitate basic science, clinical, and translational research in cancer. TIES uses a sophisticated concept based search to retrieve pathology and radiology reports containing concepts of interest.  Plans include enabling virtual slides and tissue microarray creation. The current participants in the network are University of Pittsburgh, University of Pennsylvania, Augusta University, Roswell Park Cancer Institute, Thomas Jefferson University and Stony Brook University.  +
- +
-This work is funded by grant [[https://projectreporter.nih.gov/project_info_description.cfm?aid=9324915|U24 CA180921]] from NCI, NIH. +
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- +
-==== The Pittsburgh Genome Resource Repository (PGRR) ==== +
-{{ wiki:pgrr_transparent.png?250x0}} +
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-The [[http://www.pgrr.pitt.edu/|Pittsburgh Genome Resource Repository (PGRR)]] provides data management and computing infrastructure to support investigation using The Cancer Genome Atlas (TCGA). TCGA is a “comprehensive and coordinated effort to accelerate the understanding of the molecular basis of cancer through the application of genome analysis technologies, including large-scale genome sequencing”, and is funded by the National Cancer Institute. PGRR processes data and metadata available from TCGA to provide a Pitt-specific ‘snapshot’ of the data and tools for use of this data in a secured environment. +
- +
-This work is funded by the [[http://www.ipm.pitt.edu//|Institute for Personalized Medicine (IPM)]] and the [[https://upci.upmc.edu/|University of Pittsburgh Cancer Institute (UPCI)]]. +
- +
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-==== Genomics Research and Innovation Network (GRIN) ==== +
- +
-Genomics Research and Innovation Network (GRIN) is a federated network that is developing two portals for researchers: (A) Prep-to- research portal. Investigators can execute genotype, phenotype, or combined genotype/phenotype queries, and receive aggregate results in real time; and (B) Study portal. With proper approvals, patient-level data are readily transferred to a cloud-hosted environment. +
- +
-This work is funded by a [[https://projectreporter.nih.gov/project_info_description.cfm?aid=9818382|U01 grant]] from the NCATS, NIH. +
- +
  
 +The [[http://mesotissue.org/|National Mesothelioma Virtual Bank (NMVB)]] is a virtual biospecimen registry designed to support and facilitate basic science, clinical, and translational research that will advance understanding of mesothelioma pathophysiology with the goal of expediting the discovery of preventive measures, novel therapeutic interventions, and ultimately, cures for mesothelioma. The current participants in the virtual bank are University of Pittsburgh, University of Pennsylvania, NYU Langone Medical Center, Roswell Park Cancer Institute and University of Maryland.
  
 +This work is funded by grant [[https://projectreporter.nih.gov/project_info_description.cfm?aid=8931767|U24 OH010873]] from NIOSH, NIH.